I've been running 100LL in my junk for tuning purposes. I've probably run though about 8 gallons total.
Occassionally my LC-1 is going dead. What I mean by that is that it completely stops reading. Wiggling stuff, checking connections, resetting doesn't seem to help. Let it sit for a few minutes and it's back in business.

I know that leaded gas isn't good for 02 sensors and will significantly decrease their lifespan.. Are the symptoms I'm seeing normal for use with leaded gas, or should I be looking for an electrical glitch between the LC-1 and my stand alone EFI?

 

could be either thing, or your just getting to hot and are running leaded gas, what are your egt's around ?? i dont see how it could be wirring unless its grounding out on metal somewhere.